Over the past 20 years, Japan has actively implemented various mental health strategies, including educational and training initiatives based on self-care and line-care, as well as efforts to improve workplace environments. Research in this area has expanded, yielding substantial evidence on the effectiveness of these mental health interventions at work. The Stress Check Program, introduced in 2015, mandates that workplaces with 50 or more employees must conduct the Stress Check Program and provide opportunities for high-stress individuals to receive interviews. The program also encourages the use of group analysis results to inform workplace practices, although disparities in mental health measures persist across different workplace sizes. Despite advancements in workplace mental health interventions, applications for work-related mental health compensation continue to rise, highlighting the need for broader implementation of mental health strategies and improvements in workers’ mental health across Japan. Recent research and practice have increasingly focused on factors beyond stress, such as organizational influences and motivation, which affect mental health. This shift underscores the growing importance of applying industrial and organizational psychology research and enhancing collaboration in industrial stress studies.